Treat urethritis promptly, while test results are pending. Table 124-4 summarizes the steps in management of sexually active men with urethral discharge and/or dysuria. Table 124-4 Management of Urethral Discharge in Men Usual causes Usual initial evaluation Chlamydia trachomatis pyuria Neisseria gonorrhoeae Demonstration of urethral discharge or Exclusion of local or systemic Mycoplasma genitalium complications Ureaplasma urealyticum Urethral Gram's stain to confirm urethritis, detect gram-negative diplococci Trichomonas vaginalis Test for N. gonorrhoeae, C. trachomatis Herpes simplex virus Initial Treatment for Patient and Partners Treat (unless excluded): gonorrhea plus Treat chlamydial infection: Ceftriaxone, 125 mg IM; or Azithromycin, 1 g PO; or Cefpodoxime, 400 mg PO; or 7 days .
