After a diabetes-related LEA has been reported to be as low as 28% to 31% (169, 170). Persons with renal failure or more proximal levels of amputation have a poor prognosis and higher mortality rate. Those who undergo a diabetesrelated amputation have a 40% to 50 % chance of undergoing a contralateral amputation within 2 years (36, 171, 172). ASSESSMENT OF THE DIABETIC FOOT (Pathway 1) The pedal manifestations of diabetes are well documented and potentially limb-threatening when left untreated. Recognition of risk factors and treatment of diabetic foot disorders require the skill of a specialized practitioner to diagnose,.