Descriptors for these considerations (62, 290, 291). For example, the University of Texas San Antonio (UTSA) system (Table 6) associates lesion depth with both ischemia and infection (290). This system has been validated and is generally predictive of outcome, since increasing grade and stage of wounds are less likely to heal without revascularization or amputation (290, 293). The UTSA system is now widely used in many clinical trials and diabetic foot centers. Another hybrid system, the PEDIS system, evaluates five basic characteristics: perfusion, extent/size, depth/tissue loss, infection and sensation (294) (Table 7). While this system has yet to be.
