A Dictionary of Genetics phần 10

Tham khảo tài liệu 'a dictionary of genetics phần 10', ngoại ngữ, ngữ pháp tiếng anh phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả | 532 APPENDIX C CHRONOLOGY I. Zaenen and four colleagues discover the tumor-inducing plasmid of the crown gall bacterium. K. M. Murray and N. E. Murray manipulate the recognition sites for restriction endonucleases in lambda X bacteriophage so that its chromosome can be used as a receptor site for restriction fragments from foreign DNAs. Lambda thus becomes a cloning vehicle. A. Tissieres H. K. Mitchell and U. M. Tracy find that heat shocks result in the synthesis of six new proteins in Drosophila. These are also synthesized by tissues that do not have polytene chromosomes. B. Dujon P. P. Slonimski and L. Weill propose a model for recombination and segregation of mitochondrial genomes in Saccharomyces cerevisiae. According to it mtDNA molecules are present in the zygote cell in multiple copies. These pair at random and during any mating cycle a segment from one parent can exchange with that from a second parent mtDNA yielding recombinant units. R. D. Kornberg proposes that chromatin is built up of repeated structural units of 200 base pairs of DNA and two each of the histones H2A H2B H3 and H4. These structures which are later called nucleosomes are isolated by M. Noll. A. L. Olins and D. E. Olins publish the first electron micrographs of chromatin spreads from nuclei that show nucleosomes. B. Ames develops a rapid screening test for detecting mutagenic and possibly carcinogenic compounds. S. Brenner describes methods for inducing isolating and mapping mutations in the nematode Caenorhabditis elegans. R. W. Hedges and A. E. Jacob discover in E. coli that ampicillin-resistance genes can be transferred between plasmids that show no DNA homology. The agent responsible is a mobile DNA sequence which they named a transposon. J. Ott invents the first computer program LIPED for the efficient computation of lod scores. C. A. Hutchison and three colleagues demonstrate the maternal inheritance of mitochondrial DNA in horse-donkey hybrids. G. L. Stebbins publishes Flowering .

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