Tuyển tập các nghiên cứu khoa học của trường đại học Huế đề tài: Nghiên cứu về sự phổ biến của HBsAg seropositivity ở những người ở Thừa Thiên Huế. | JOURNAL OF SCIENCE Hue University N0 61 2010 STUDY ON THE PREVALENCE OF HBsAg SEROPOSITIVITY IN PEOPLE IN THUA THIEN HUE PROVINCE Ngo Viet Loc College of Medicine and Pharmacy Hue University SUMMARY Hepatitis B infection is caused by the hepatitis B virus HBV . About 400 million people across the world are chronically infected by the hepatitis B virus. Hepatitis B is a leading cause of chronic hepatitis cirrhosis and hepatocellular carcinoma accounting for 1 million deaths annually. In Asia the rate of hepatitis B surface antigen HBsAg carriage in the general population ranges from 2 to 20 . The aim of this study were to determine the percentage of positive hepatitis B surface antigen of people aged 6 and over in Thua Thien Hue Province. Methodology A cross sectional descriptive study was conducted from 2006 to 2008 including 2 525 people aged 6 years and over who were living in four ecological areas of Thua Thien Hue Province mountainous low land coastal and Hue city urban . These people were detected the hepatitis B surface antigen HBsAg by enzyme immunoassay and interviewed by questionnaire. Results The overall prevalence of the HBsAg positive was analysis of sex in the group of HBsAg positive the prevalence of HBsAg positive in females was higher than in males and HBsAgpositive and age groups the HBsAgpositive prevalence was the highest in the age groups of 20 - 19 and 31 - 40 . HBsAg positive and occupation the highest prevalence of HBsAg positive was found among manual workers. HBsAg positive and ecological areas The prevalence of HBsAg positive in coastal area was the highest . Conclusion The prevalence of the HBsAg positive of people aged 6 and over in Thua Thien Hue province was . Accordingly public measures to control HBV infection are needed. Key word Infection of HBV 1. Introduction Hepatitis B virus HBV infection is a global public health problem and it has been estimated by the World Health Organization