Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học Journal of Biology đề tài: The gene complement of the ancestral bilaterian - was Urbilateria a monster? | Journal of Biology Minireview The gene complement of the ancestral bilaterian - was Urbilateria a monster David J Miller and Eldon E Ballt Addresses ARC Centre of Excellence for Coral Reef Studies and Comparative Genomics Centre James Cook University Townsville Queensland 4811 Australia. Centre for Molecular Genetics of Development and School of Biology Australian National University Canberra ACT 2601 Australia. Correspondence David Miller. Email Abstract Expressed sequence tag analyses of the annelid Pomatoceros lamarckii recently published in BMC Evolutionary Biology are consistent with less extensive gene loss in the Lophotrochozoa than in the Ecdysozoa but it would be premature to generalize about patterns of gene loss on the basis of the limited data available. See research article http 1471-2148 9Z240. The pioneers of pyrosequencing have a lot to answer for. The availability of next generation DNA sequencers has provided zoologists with unforeseen opportunities to address many basic evolutionary issues and for those of us whose interests lie beyond the model organisms these are indeed interesting times. Not so long ago the costs of large-scale expressed sequence tag EST analyses were prohibitive but the recent development of the fast and relatively cheap 454 Illumina and SOLiD technologies is enabling large-scale transcriptome analysis and potentially whole-genome analysis to be applied to a wide range of animals providing insights into evolutionary issues that were once considered essentially intractable. One important and controversial issue that can now be addressed is the gene complement of Urbilateria. It is clear that this ancestor of all bilateral animals had a genome resembling that of a modern vertebrate but which also contained some genes lost from modern vertebrates raising the issue of just how many genes were present in the ancestor. In this respect EST studies on lophotrochozoans such as that .
