Tuyển tập các báo cáo nghiên cứu khoa học quốc tế về bệnh thú y đề tài: Calcium metabolism in cows receiving an intramuscular injection of 1,25-dihydroxyvitamin D3 combined with prostaglandin F2?? closely before parturition | J. Vet. Sci. 2005 6 2 165-167 JOURNAL OF Short Communication Veterinary Science Calcium metabolism in cows receiving an intramuscular injection of 1 25-dihydroxyvitamin D3 combined with prostaglandin F2a closely before parturition Norio Yamagishi Yu Ayukawa2 Inhyung Lee Kenji Oboshi Yoshihisa Naito4 Research Center for Animal Hygiene and Food Safety and2 Department of Veterinary Clinical Sciences Obihiro University of Agriculture and Veterinary Medicine Obihiro Hokkaido 080-8555 Japan Department of Neuroscience and Cell Biology University of Texas Medical Branch 301 University Boulevard Galveston TX 77555-1069 UsA Department of Veterinary Clinical Medicine Faculty of Agriculture Iwate University Morioka Iwate 020-8550 Japan To determine the effect of exogenous 1 25-dihydroxyvitamin Dj 1 25 OH 2DJ combined with induced parturition on calcium Ca metabolism cows received a single intramuscular injection of 1 25 OH 2D3 and prostaglandin Fto PGF closely before calving. Ten late-pregnant multiparous Holstein cows were assigned to 1 25 OH 2D3 group five treated with both 1 25 OH 2D3 and PGF and control group five treated with PGF J. 1 25 OH 2D3 group showed an increase in plasma Ca concentration around parturition whereas control group revealed a decrease in plasma Ca level. Plasma Ca concentration in 1 25 OH 2D3 group were significantly higher than that in control group during to 3 days after parturition. Key words cow calcium 1 25-dihydroxyvitamin D3 hypocalcemia parturition 1 25-dihydroxyvitamin D3 1 25 OH 2D3 a physiologically active form of vitamin D metabolites has been used to elevate plasma calcium Ca concentration during 1 to 4 days post-injection and thereby prevent parturient paresis parturient hypocalcemia in dairy cows 2 4 5 . This metabolite has the advantage of a shorter biological life than vitamin D3 therefore toxicity problems are reduced 9 . The shorter biological life also requires a more accurate prediction of the time of parturition for full .
