Tuyển tập các báo cáo nghiên cứu khoa học quốc tế về bệnh thú y đề tài: Hepatic encephalomyelopathy in a calf with congenital portosystemic shunt (CPSS) | J. Vet. Sci. 2008 9 1 113-115 Case Report JOURNAL OF Veterinary Science Hepatic encephalomyelopathy in a calf with congenital portosystemic shunt CPSS 11 2 3 4 11 Valeria Café Marẹal Anna Oevermann Tim Bley Patrizia Pfister Julien Miclard institute of Animal Pathology Vetsuisse Faculty University of Berne Laenggassstr. 122 CH-3001 Berne Switzerland 2Institute of Neuropathology NeuroCenter Vetsuisse Faculty University of Berne Bremgartenstr. 109a Postfach 8466 CH-3001 Berne Switzerland 3Department of Clinical Veterinary Medicine Division of Clinical Neurology Vetsuisse Faculty University of Berne Laenggassstr 128 CH-3012 Berne Switzerland 4Clinic for Ruminants Vetsuisse Faculty University of Berne Bremgartenstr 109a CH-3012 Berne Switzerland A 4-month-old female Holstein Friesian calf was referred to the Veterinary Teaching Hospital University of Berne Switzerland for evaluation of ataxia weakness apathy and stunted growth. Clinical examination revealed generalized ataxia propioceptive deficits decreased menace response and sensibility. Postmortem examination did not reveal macroscopic changes of major organs. Histologically the brain and the spinal cord lesions were characterized by polymicrocavitation preferentially affecting the white matter fibers at the junction of grey and white matter and by the presence of Alzheimer type II cells. The liver revealed lesions consistent with a congenital portosystemic shunt characterized by increased numbers of arteriolar profiles and hypoplasia to absence of portal veins. The pathological investigations along with the animal history and clinical signs indicated a hepatic encephalomyelopathy due to a congenital portosystemic shunt. Keywords hepatic encephalopathy Holstein Friesian cattle pathological investigation portosystemic shunt Hepatic encephalopathy HE refers to a spectrum of neuropsychiatric abnormalities associated with significant liver dysfunction and is commonly described in humans and domestic carnivores 5 6 . In
