Tuyển tập các báo cáo nghiên cứu khoa học quốc tế về bệnh thú y đề tài: Effects of mosapride on motility of the small intestine and caecum in normal horses after jejunocaecostomy | J. Vet. Sci. 2009 10 2 157-160 DOI JOURNAL OF Veterinary Science Effects of mosapride on motility of the small intestine and caecum in normal horses after jejunocaecostomy 1 -2 .2 2 3 2 Kouichi Okamura Naoki Sasaki Takuya Kikuchi Aya Murata Inhyung Lee Haruo Yamada Hisashi Inokuma2 1The United Graduate School of Veterinary Sciences Gifu University 1-1 Yanago Gifu-shi 501-1193 Japan 2Department of Veterinary Clinical Science Obihiro University of Agriculture Veterinary Medicine Inada Obihiro Hokkaido 080-8555 Japan 3Department of Veterinary Surgery and Anesthesiology College of Veterinary Medicine Seoul National University Seoul 151-742 Korea The purpose of the present study was to evaluate the prokinetic effects of mosapride with non-invasive assessment of myoelectrical activity in the small intestine and caecum of healthy horses after j ejunocaecostomy. Six horses underwent celiotomy and jejunocaecostomy and were treated with mosapride treated group at mg kg per osos once daily for 5 days after surgery. The other six horses did not receive treatment and were used as controls non-treated group . The electrointestinography EIG maximum amplitude was used to measure intestinal motility. Motility significantly decreased following surgery. In the treated group the EIG maximum amplitude of the small intestine was significantly higher than in the controls from day 6 31 after treatment. These findings clearly indicate that mosapride could overcome the decline of intestinal motility after jejunocaecostomy in normal horses. Keywords horse ileus mosapride small intestine Introduction Jejunocaecostomy is performed in horses if the distal ileum requires resection due to strangulating obstruction and or stenosis or bypass 6-8 . However after jejunocaecostomy the horses experienced reduced intestinal motility with postoperative ileus resulting in death 2 5 12 . From rodent studies it is apparent that at least three major mechanisms are involved in .
