Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: Computerized two-lead resting ECG analysis for the detection of coronary artery stenosis. | Int. J. Med. Sci. 2007 4 249 Research Paper International Journal of Medical Sciences ISSN 1449-1907 2007 4 5 249-263 Ivyspring International Publisher. All rights reserved Computerized two-lead resting ECG analysis for the detection of coronary artery stenosis Eberhard Grube 1 Andreas Bootsveld 2 Seyrani Yuecel 1 Joseph T. Shen 3 Michael Imhoff 4 1. Department of Cardiology and Angiology Heart Center Siegburg Klinikum Siegburg Ringstrasse 49 D-53721 Siegburg Germany 2. Department of Cardiology Evangelisches Stift St. Martin Johannes-Mueller-Strasse 7 D-56068 Koblenz Germany 3. Premier Heart LLC 14 Vanderventer Street Port Washington NY 11050 USA 4. Department for Medical Informatics Biometrics and Epidemiology Ruhr-University Bochum Postbox D-44780 Bochum Germany Correspondence to Michael Imhoff MD PhD Am Pastorenwaldchen 2 D-44229 Dortmund Germany. Phone 49-231-973022-0 Fax 49-231-973022-31 e-mail mike@ Received Accepted Published Background Resting electrocardiogram ECG shows limited sensitivity and specificity for the detection of coronary artery disease CAD . Several methods exist to enhance sensitivity and specificity of resting ECG for diagnosis of Cad but such methods are not better than a specialist s judgement. We compared a new computer-enhanced resting ECG analysis device 3DMP to coronary angiography to evaluate the device s accuracy in detecting hemodynamically relevant CAD. Methods A convenience sample of 423 patients without prior coronary revascularization was evaluated with 3DMP before coronary angiography. 3DMP s sensitivity and specificity in detecting hemodynamically relevant coronary stenosis as diagnosed with coronary angiography were calculated as well as odds ratios for the 3DMP severity score and coronary artery disease risk factors. Results 3DMP identified 179 of 201 patients with hemodynamically relevant stenosis sensitivity specificity . The positive and negative .
