Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: Clinical Profiles of Chronic Hepatitis C in a Major County Medical Center Outpatient Setting in United States. | Int. J. Med. Sci. 2004 1 2 92-100 92 Research paper Received Accepted Published Abstract Key words Author biography Corresponding address International Journal of Medical Sciences ISSN 1449-1907 2004 1 2 92-100 2004 Ivyspring International Publisher. All rights reserved Clinical Profiles of Chronic Hepatitis C in a Major County Medical Center Outpatient Setting in United States Ke-Qin Hu1 Huiying Yang2 Ying-Chao Lin2 Karen L Lindsay3 and Allan G Redeker3 1 Division of Gastroenterology and Hepatology University of California Irvine College of Medicine Orange CA USA 2 Division of Medical Genetics Cedars-Sinai Medical Center UCLA Los Angeles CA USA and 3 Division of GI Liver Keck School of Medicine University of Southern California Los Angeles CA USA The estimated prevalence of hepatitis C virus HCV infection in the US is . Data are limited on the clinical profile of the disease at first presentation and dynamic follow-up of ALT level especially in publicly-funded patients. This information is critical for optimal management of these patients. The present study is aimed to assess the clinical profiles of chronic hepatitis C CHC at first presentation and clinical implication of dynamic follow-up of ALT level in a county medical center setting. A total of 294 patients were selected from the population consecutively evaluated in the Hepatitis Clinic at Los Angeles County-USC Medical Center between Jan. 1990 and Dec. 1998. Ethnicity of the patients was African and . Risk factors were identifiable in of patients and injection drug use IDU represented the leading risk factor for HCV acquisition . History of alcoholism was present in . The initial clinical diagnoses were chronic hepatitis compensated cirrhosis and decompensated cirrhosis . Elevation of ALT alpha fetoprotein AFP ferritin and anti-nuclear antibody ANA titer were seen in 219 294 .