Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: A review of anatomical and mechanical factors affecting vertebral body integrity. | Int. J. Med. Sci. 2004 1 170-180 170 International Journal of Medical Sciences ISSN 1449-1907 2004 1 3 170-180 2004 Ivyspring International Publisher. All rights reserved Review Received Accepted Published A review of anatomical and mechanical factors affecting vertebral body integrity Andrew M Briggs1 2 Alison M Greig1 John D Wark2 Nicola L Fazzalari3 Kim L Bennell1 1. Centre for Health Exercise and Sports Medicine School of Physiotherapy University of Melbourne Australia. 2. Department of Medicine Royal Melbourne Hospital University of Melbourne Australia. 3. Institute of Medical and Veterinary Science South Australia. Abstract Background The aetiology of osteoporotic vertebral fracture is multifactorial and may be conceptualised using a systems framework. Previous studies have established several correlates of vertebral fracture including reduced vertebral cross-sectional area weakness in back extensor muscles reduced bone mineral density increasing age worsening kyphosis and recent vertebral fracture. Alterations in these physical characteristics may influence biomechanical loads and neuromuscular control of the trunk and contribute to changes in subregional bone mineral density of the vertebral bodies. Methods This review discusses factors that have received less attention in the literature which may contribute to the development of vertebral fracture. A literature review was conducted using electronic databases including Medline Cinahl and ISI Web of Science to examine the potential contribution of trabecular architecture subregional bone mineral density vertebral geometry muscle force muscle strength neuromuscular control and intervertebral disc integrity to the aetiology of osteoporotic vertebral fracture. Interpretation A better understanding of factors such as biomechanical loading and neuromuscular control of the trunk may help to explain the high incidence of subsequent vertebral fracture after sustaining
