Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: Characterization of N200 and P300: Selected Studies of the Event-Related Potential Salil H. Patel 1 and Pierre N. Azzam 2. | Int. J. Med. Sci. 2005 2 147 Review International Journal of Medical Sciences ISSN 1449-1907 2005 2 4 147-154 2005 Ivyspring International Publisher. All rights reserved Characterization of N200 and P300 Selected Studies of the Event-Related Potential Salil H. Patel 1 and Pierre N. Azzam 2 1. The Methodist Hospital Houston TX 77002 USA 2. Baylor College of Medicine Houston TX 77030 USA Corresponding address Salil H. Patel MD . Tel 1 713 757 7529. Fax 1 713 657 7208 Received Accepted Published The Event-Related Potential ERP is a time-locked measure of electrical activity of the cerebral surface representing a distinct phase of cortical processing. Two components of the ERP which bear special importance to stimulus evaluation selective attention and conscious discrimination in humans are the P300 positivity and N200 negativity appearing 300 ms and 200 ms post-stimulus respectively. With the rapid proliferation of high-density EEG methods and interdisciplinary interest in its application as a prognostic diagnostic and investigative tool an understanding of the underpinnings of P300 and N200 physiology may support its application to both the basic neuroscience and clinical medical settings. The authors present a synthesis of current understanding of these two deflections in both normal and pathological states. Keywords Electroencephalography EEG N2 Neuroimaging P3 Selective attention 1. Introduction The widespread adoption of electroencephalography EEG for the non-invasive assessment of cortical activity has inaugurated a distinct era in the elucidation of brain function. Due to its high temporal resolution EEG imaging of relative scalp electrical positivities and negativities may expose subtle cognitive activity. Indeed shortly after the advent of electrophysiological recording in the late 1920s physiologists readily observed discrepancies in the brainwave records of .
