Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: Effect of Acute Administration of an Herbal Preparation on Blood Pressure and Heart Rate in Humans. | Int. J. Med. Sci. 2011 8 192 International Journal of Medical Sciences 2011 8 3 192-197 Research Paper Effect of Acute Administration of an Herbal Preparation on Blood Pressure and Heart Rate in Humans John G. Seifert1 Aaron Nelson2 Julia Devonish2 Edmund R. Burke3 and Sidney J. Stohs4 1. Movement Science Human Performance Laboratory Montana State University Bozeman MT USA 2. Human Performance Laboratory St. Cloud State University St. Cloud MN USA 3. Dept of Biology Colorado University - Colorado Springs Colorado Springs CO USA 4. School of Pharmacy and Health Professions Creighton University Medical Center Omaha NE USA H Corresponding author 406-994-7154 Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License http licenses by-nc-nd . Reproduction is permitted for personal noncommercial use provided that the article is in whole unmodified and properly cited. Received Accepted Published Abstract Confusion and controversy exist regarding the cardiovascular effects of dietary supplements containing caffeine and Citrus aurantium bitter orange extract. The primary protoalkaloidal ingredient in bitter orange extract is p-synephrine which has some structural similarities to ephedrine and nor-epinehrine but exhibits markedly different pharmacokinetic and receptor binding properties. The goal of this study was to investigate the cardiovascular effects of a product containing caffeine bitter orange extract p-synephrine and green tea extract in mildly overweight individuals. Fourteen female and nine male subjects age yrs BMI volunteered in this randomized placebo-controlled crossover double-blind designed study. On day one subjects entered the laboratory following an overnight fast. Heart rate and blood pressure were recorded at 60 min. Expired air was analyzed for the next 10 min of the session. At each of .