Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài:Soluble Endothelial Selectin in Acute Lung Injury Complicated by Severe Pneumonia. | Int. J. Med. Sci. 2011 8 302 Research Paper International Journal of Medical Sciences 2011 8 4 302-308 Soluble Endothelial Selectin in Acute Lung Injury Complicated by Severe Pneumonia Daisuke Osaka1 Yoko Shibata1 x Kazunori Kanouchi2 Michiko Nishiwaki1 Tomomi Kimura1 Hiroyuki Kishi1 Shuichi Abe1 Sumito Inoue1 Yoshikane Tokairin1 Akira Igarashi1 Keiko Yamauchi1 Yasuko Aida1 Takako Nemoto1 Keiko Nunomiya1 Koji Fukuzaki1 and Isao Kubota1 1. Department of Cardiology Pulmonology and Nephrology Yamagata University School of Medicine Yamagata Japan 2. Division of Clinical Laboratory Yamagata University Hospital Yamagata Japan x Corresponding author Dr. Yoko Shibata 2-2-2 Iida-Nishi Yamagata City Yamagata 990-9585 Japan. Telephone 81-23-628-5302 FAX 81-23-628-5305 Email shibata@ Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License http licenses by-nc-nd . Reproduction is permitted for personal noncommercial use provided that the article is in whole unmodified and properly cited. Received Accepted Published Abstract Background Pneumonia is still one of the most frequent causes of death in the elderly. Complication of acute lung injury ALI acute respiratory distress syndrome ARDS by pneumonia makes patients very ill due to severe respiratory failure. Biomarkers that can discriminate the presence of complicating ALI ARDS are required for early detection. The aim of this research was to investigate whether soluble endothelial selectin sES could be a biomarker for ALI. Methods Serum sES levels were measured in 27 pneumonia patients who were enrolled between April 2006 and September 2007. Among these patients six had ALI or a condition that was clinically comparable to ALI cALI . All patients who were enrolled were successfully treated and survived. Results Circulating sES levels were elevated in pneumonia patients with ALI .
