Báo cáo y học: "Translational Medicine and Reliability of Single-Nucleotide Polymorphism Studies: Can We Believe in SNP Reports or Not"

Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: Translational Medicine and Reliability of Single-Nucleotide Polymorphism Studies: Can We Believe in SNP Reports or Not? | Int. J. Med. Sci. 2011 8 492 o IVYSPRING . . I fl. International Journal of Medical Sciences 2011 8 6 492-500 Research Paper Translational Medicine and Reliability of Single-Nucleotide Polymorphism Studies Can We Believe in SNP Reports or Not Antonis Valachis1 2 Davide Mauri2 3 x Christodoulos Neophytou2 Nikolaos P. Polyzos2 4 Lampriani Tsali5 Antonios Garras6 Evangelos G. Papanikolau4 1. Onkologkliniken Sormland Malarsjukhuset Eskilstuna Sweden 2. PACMeR department of. Medical Oncology Athens Greece 3. Department of Medical Oncology General Hospital of Lamia Greece 4. Centre for Reproductive Medicine Free University of Brussels Brussels Belgium 5. PACMeR associate researcher dept. Internal Medicine Athens Greece 6. Department of Obstetrics and Gynaecology University General Hospital of Larisa Greece H Corresponding author Davide Mauri Dept. Med. Oncol. Gen. Hosp. of Lamia Daravelia 27 TK 35100 Lamia Greece. Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License http licenses by-nc-nd . Reproduction is permitted for personal noncommercial use provided that the article is in whole unmodified and properly cited. Received Accepted Published Abstract Background The number of genetic association studies is increasing exponentially. Nonetheless genetic association reports are prone to potential biases which may influence the reported outcome. Aim We hypothesized that positive outcome for a determined polymorphism might be over-reported across genetic association studies analysing a small number of polymorphisms when compared to studies analysing the same polymorphism together with a high number of other polymorphisms. Methods We systematically reviewed published reports on the association of glutathione s-transferase GST single-nucleotide polymorphisms SNPs and cancer outcome. Result We identified 79 eligible trials. Most of

Không thể tạo bản xem trước, hãy bấm tải xuống
TÀI LIỆU XEM NHIỀU
TỪ KHÓA LIÊN QUAN
TÀI LIỆU MỚI ĐĂNG
289    46    1    29-03-2024
170    68    2    29-03-2024
Đã phát hiện trình chặn quảng cáo AdBlock
Trang web này phụ thuộc vào doanh thu từ số lần hiển thị quảng cáo để tồn tại. Vui lòng tắt trình chặn quảng cáo của bạn hoặc tạm dừng tính năng chặn quảng cáo cho trang web này.