Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Gender difference in QTc prolongation of people with mental disorders. | Annals of General Hospital Psychiatry Primary research BioMed Central Open Access Gender difference in QTc prolongation of people with mental disorders Hiroto Ito 1 Toshiaki Kono2 Shigenobu Ishida3 and Hisao Maeda3 Address National Institute of Public Health 2-3-6 Minami Wako Saitama 351-0197 Japan 2Department of Psychiatry Division of Neuroscience Graduate School of Medicine The University of Tokyo Japan and 3Department of Neuropsychiatry Kurume University School of Medicine Japan Email Hiroto Ito - ito@ Toshiaki Kono - tkono-tky@ Shigenobu Ishida - ishidas@ Hisao Maeda - maehisa@ Corresponding author Published 13 February 2004 Received 20 June 2003 Accepted 13 February 2004 Annals of General Hospital Psychiatry 2004 3 3 This article is available from http content 3 l 3 2004 Ito et al licensee BioMed Central Ltd. This is an Open Access article verbatim copying and redistribution of this article are permitted in all media for any purpose provided this notice is preserved along with the article s original URL. Abstract Background We examined gender difference in QTc interval distribution and its related factors in people with mental disorders. Methods We retrospectively reviewed medical charts of patients discharged from a university psychiatric unit between November 1997 and December 2000. Subjects were 328 patients 145 males and l83 females taking psychotropics at their admission. We examined patient characteristics medical history diagnosis and medication before admission. Results Mean QTc interval was SD . QTc intervals in females were significantly longer than those in males. QTc of females without comorbidity was significantly longer than that of males. Conclusion The influence of gender difference on QTc prolongation in people with mental disorders merits further research. Background QT interval prolongation is regarded as an indicator of potential for .
