Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Role of Leukotriene Receptor Antagonists in the Treatment of Exercise-Induced Bronchoconstriction: A Review. | Review Article Role of Leukotriene Receptor Antagonists in the Treatment of Exercise-Induced Bronchoconstriction A Review George S. Philteos MD FRCP C Beth E. Davis BSc Donald W. Cockcroft MD FRCP C Darcy D. Marciniuk MD FRCP C Abstract Asthma is a very common disorder that still causes significant morbidity and mortality. A high percentage of individuals with asthma also experience exercise-induced bronchoconstriction EIB . This article reviews the current literature and updates the reader on the safety efficacy and clinical applications of leukotriene modifiers in the treatment of EIB. Asthma affects 14 to 15 million people in the United States and is responsible for more than 100 million days of restricted activity more than 5 000 deaths and 470 000 hospitalizations each Previously characterized as a disease of airway smooth muscle asthma is currently defined by the National Heart Lung and Blood Institute as a chronic inflammatory disorder of the airways in which many cells and cellular elements play a role in particular mast cells eosinophils T lymphocytes macrophages neutrophils and epithelial cells. 2 Exercise-induced bronchoconstriction EIB occurs in approximately 80 to 90 of individuals with asthma and in approximately 11 of the general population without otherwise symp- G. S. Philteos B. E. Davis D. W. Cockcroft D. D. Marciniuk Division of Respiratory Medicine Department of Medicine University of Saskatchewan Royal University Hospital Saskatoon Saskatchewan D. D. Marciniuk Lung Association of Saskatchewan COPD Professorship D. W. Cockcroft Lung Association of Saskatchewan Ferguson Professorship Correspondence to Dr. D. D. Marciniuk Division of Respiratory Medicine University of Saskatchewan Ellis Hall Rm. 545 5th Floor Saskatoon SK S7N 0W8 tomatic 4 This article reviews the current literature and updates the reader on the safety efficacy and clinical applications of leukotriene modifiers in the treatment of EIB. Role of Leukotrienes in .
