Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Critical Aspects of the History of Occupational Asthma. | Review Article Critical Aspects of the History of Occupational Asthma Susan M. Tarlo MB BS FRCP C Abstract The medical history is the gateway to the diagnosis of occupational asthma. The medical history should indicate whether a patient s asthma began during a work period and whether the asthma worsens during work periods or improves on days when the patient is off work or on holidays. A suspicion of sensitizer-induced occupational asthma will increase if the patient was exposed to a recognized respiratory sensitizer in the workplace at the time of the onset of symptoms or if the patient had associated symptoms of allergic rhinitis and conjunctivitis. A history of accidental high respiratory irritant exposure shortly before the initial onset of symptoms would raise the possibility of irritant-induced occupational asthma. Although such features of the history are sensitive indicators of occupational asthma they are not specific and should therefore be followed by further investigations to confirm the diagnosis of asthma and its relation to the workplace exposure. The earlier the diagnosis is suspected and investigated the better the outcome is likely to be for the patient. Occupational asthma OA is defined as asthma that is due to causes and conditions attributable to a particular occupational environment and not to stimuli encountered outside the It has been estimated to account for 10 to 15 of all adult-onset It is most often caused by sensitization to a workplace substance via immunoglobulin E IgE antibody responses or other immunologic mechanisms but can also be due to high-level irritant exposure in about 5 of all cases irritant-induced asthma 3 of which the clearest example is reactive airways dysfunction syndrome RADS 4 . This article will not discuss work-aggravated asthma which is the aggravation of underlying asthma by factors in the workplace such as exertion cold air dusts smoke or fumes. . Tarlo Toronto Western Hospital Gage .
