Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Psychological Factors in Asthma. | ORIGINAL ARTICLE Psychological Factors in Asthma Ryan J. Van Lieshout MD and Glenda MacQueen MD PhD FRCPC Asthma has long been considered a condition in which psychological factors have a role. As in many illnesses psychological variables may affect outcome in asthma via their effects on treatment adherence and symptom reporting. Emerging evidence suggests that the relation between asthma and psychological factors may be more complex than that however. Central cognitive processes may influence not only the interpretation of asthma symptoms but also the manifestation of measurable changes in immune and physiologic markers of asthma. Furthermore asthma and major depressive disorder share several risk factors and have similar patterns of dysregulation in key biologic systems including the neuroendocrine stress response cytokines and neuropeptides. Despite the evidence that depression is common in people with asthma and exerts a negative impact on outcome few treatment studies have examined whether improving symptoms of depression do in fact result in better control of asthma symptoms or improved quality of life in patients with asthma. Key words asthma depression pathophysiology treatment Psychological factors may influence the symptoms and management of asthma and numerous pathways may contribute to the links between asthma and psychiatric disease states such as depression. The notion that emotional stress can precipitate or exacerbate acute and chronic asthma1 has been recognized anecdotally for many years. Psychological barriers such as faulty symptom attribution adoption or rejection of the sick role and low self-esteem may negatively impact treatment adherence. Conversely the presence of a chronic and potentially life-threatening illness may exert enough stress that an anxiety or depressive disorder emerges in vulnerable patients. As a consequence epidemiologic associations between major depressive disorder MDD and asthma might be apparent but not reflect a .
