Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: QTc and psychopharmacs: are there any differences between monotherapy and polytherapy. | Annals of General Psychiatry BioMed Central Primary research QTc and psychopharmacs are there any differences between monotherapy and polytherapy Jadranka Culav Sumic Vesna Barick Petar Bilic z Miroslav Hercegk Mirna Sisek-Spremt and Vlado Jukic Open Access Address Vrapce Psychiatric Hospital Bolnicka 32 10090 Zagreb Croatia Email Jadranka Culav Sumic - damir_sumic@ Vesna Baric - Petar Bilic - Miroslav Herceg - Mirna Sisek-Sprem - Vlado Jukic - Corresponding author tEqual contributors Published 3 May 2007 Received 22 December 2006 Annals of General Psychiatry 2007 6 13 doi 1744-859X-6-1 3 Accepted 3 May 2007 This article is available from http content 6 1 13 2007 Sumic et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Some psychotropic drugs are connected with prolongation of QT interval increased risk of cardiac arrhythmias and greater incidence of sudden death especially when used in combination. Concomitant use of antipsychotics and antidepressants is not rare in our clinical practice. The study compares the length of QT interval in patients on monotherapy with an antipsychotic or an antidepressant and patients taking polytherapy an antipsychotic agent combined with an antidepressant . Methods Sixty-one hospitalized women who met the ICD-10 criteria for schizophrenia schizoaffective psychosis delusional disorder and mood disorder were included in the study. The monotherapy group was consisted of thirty-two women treated with an antipsychotic or an antidepressant while the polytherapy group was .
