Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: The relationship between antipsychotic medication adherence and patient outcomes among individuals diagnosed with bipolar disorder: a retrospective study. | Annals of General Psychiatry BioMed Central Primary research The relationship between antipsychotic medication adherence and patient outcomes among individuals diagnosed with bipolar disorder a retrospective study Maureen J Lage1 and Mariam K Hassan 2 Open Access Address 1Health Metrics Outcomes Research Groton CT USA and 2AstraZeneca Pharmaceuticals LP Wilmington DE USA Email Maureen J Lage - lagemj@ Mariam K Hassan - Corresponding author Published 18 February 2009 Received 18 August 2008 Annals of General Psychiatry 2009 8 7 doi 1744-859X-8-7 Accepted 18 February 2009 This article is available from http content 8 1 7 2009 Lage and Hassan licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Reducing hospitalizations and emergency room visits is important to improve patient outcomes. This observational study examined the association between adherence to antipsychotics and risk of hospitalizations and emergency room ER visits among patients with bipolar disorder. Methods Claims data from commercial healthcare plans Pharmetrics January 2000 to December 2006 for patients with bipolar disorder receiving an antipsychotic prescription were examined. Adherence was analyzed over a 12-month follow-up period after the receipt of first prescription of an antipsychotic. Adherence to antipsychotics was measured by the medication possession ratio MPR . The MPR was calculated as the number of days that an antipsychotic medication was filled as compared with the total number of days during the follow-up period. Logistic stepwise regressions examined the association between achievement of various adherence goals and patient outcomes .
