Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Analysis of the recurrence risk factors for the patients with hepatocellular carcinoma meeting University of California San Francisco criteria after curative hepatectomy | Soong et al. World Journal of Surgical Oncology 2011 9 9 http content 9 1 9 5 t WORLD JOURNAL OF SURGICAL ONCOLOGY RESEARCH Open Access Analysis of the recurrence risk factors for the patients with hepatocellular carcinoma meeting University of California San Francisco criteria after curative hepatectomy Ruey-Shyang Soong Ming-Chin Yu Kun-Ming Chan Hong-Shiue Chou Ting-Jung Wu Chen-Fang Lee Tsung-Han Wu Wei-Chen Lee Introduction Hepatocellular carcinoma HCC is one of the most common cancers worldwide especially in the Asia pacific area 1 . Liver transplantation is theoretically the best option because it cures both the tumor and the underlying liver disease. The overall survival rate at 5 years after liver transplantation was around 70-75 2 . In contrast 5-year survival rates after liver resection were only 40 to 65 and the 10-year survival rate was 29 . The high incidence of HCC recurrence following liver resection is a serious issue. The recurrent rate is as high as 50-60 at 3 years and 70-100 at 5 years. This high recurrent rate precludes long-term tumor-free survival of the patients with liver resection for HCC. However liver transplantation is limited by a shortage of graft availability. Liver transplantation also has high perioperative risk and long-term problems such as graft rejection and infections 3 . Therefore liver resection is still the primary selection treatment for many HCC patients especially in areas lacking deceased liver. Nevertheless there is no doubt that for HCC liver transplantation is a superior treatment option to liver resection where long-term tumor-free survival is concerned. Adult-to-adult living donor liver transplantation is a well-established technique now. Liver transplantation for patients with HCC becomes feasible if a living donor wishes to donate part of the liver to save a member of the family. To optimize the benefit of living donor liver transplantation for HCC patients the Correspondence weichen@ .
