Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: A case report of male breast cancer in a very young patient: What is changing | Madeira et al. World Journal of Surgical Oncology 2011 9 16 http content 9 1 16 WORLD JOURNAL OF SURGICAL ONCOLOGY CASE REPORT Open Access A case report of male breast cancer in a very young patient What is changing 1 3 Marcelo Madeira 1 André Mattar1 Rodrigo José Barata Passos Caroline Dornelles Mora Luiz Henrique Beralde Vilar Mamede2 Viviane Hatsumi Kishino2 Thomas Zurga Markus Torres2 Andressa Fernandes Rodrigues de Sá2 Roberto Euzébio dos Santos 2 3 Luiz Henrique Gebrim1 3 Abstract Male breast cancer accounts for 1 of all breast cancer cases and men tend to be diagnosed at an older age than women mean age is about 67 years . Several risk factors have been identified such as genetic and hormonal abnormalities. The present study reported the case of a 25-year-old man who was diagnosed with an advanced invasive ductal carcinoma however he did not have any important risk factors. Even though more data is emerging about this disease more efforts to understand risk factors treatment options and survival benefits are needed. In this case we discussed the risk factors as well as the impaired fertility associated with breast cancer therapies. Background Breast cancer in men is rare and it accounts for about 1 of all malignant breast neoplasm cases 1 2 . The estimated incidence is 1 case for each 100 000 men. In the United States about 1 910 new cases were diagnosed in 2009 and 440 of these cases resulted in death 3 . Among the histologic types invasive ductal carcinoma is the most prevalent breast cancer in males with an incidence varying from 65 to 95 2 4 . Male breast cancer has unimodal age-frequency distribution with a peak incidence at 71 years old. Conversely female breast cancer has a bimodal age-frequency distribution with early-onset and late-onset peak incidences at 52 and 72 years old respectively 5 . This study examined a 25-year-old man without important risk factors who was diagnosed with invasive ductal carcinoma. Although it is rare