Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Vaginal treatment of endometrial cancer: role in the elderly | Moscarini et al. World Journal of Surgical Oncology 2011 9 74 http content 9 1 74 7 Q WORLD JOURNAL OF SURGICAL ONCOLOGY RESEARCH Open Access Vaginal treatment of endometrial cancer role in the elderly Massimo Moscarini Enzo Ricciardi Alessandro Quarto Paolo Maniglio and Donatella Caserta Abstract Background To compare abdominal hysterectomy the most currently used for treating cancer of the endometrium to the vaginal hysterectomy in term of survival morbidity and failure rates. Methods We retrospectively analyzed 68 cases divided into two sub-groups. A study group of 31 cases received vaginal surgery a control group of 37 cases was treated with a laparotomy. Mean operative time median hospital stay intra- and post-operative complications DFS and OS time as well as occurrence of local or distant recurrences have been evaluated and reported. Cases included patients with a higher rate of medical morbidities p than controls. Results Mean age was and years in the vaginal V group and abdominal A group respectively. Mean operative time was longer for the group A. Group V patients had a lower mean post-operative hospital stay p . Differences in the two groups regarding intra- and post-operative complications occurrence of local or distant recurrences and DFS time were not statistically significant. Disease specific survival time at 5 years scored 97 for group V and 97 for group A. Conclusions Results show how vaginal approach had a similar outcome in selected patients. Vaginal surgery could therefore be the proper choice in patients with early stages and lower surgical risk in addition to elderly patients exposed to a higher surgical risk. Keywords Endometrial Cancer Surgery Elderly Patients Hysterectomy Prognosis Background Endometrial carcinoma is the most common gynecological malignancy in western countries with an incidence of 15-20 per women per year. In 2006 41200 new cases were reported only in the United States with half of
