Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Late local recurrence of dermatofibrosarcoma protuberans in the skin of female breast | Dragoumis et al. World Journal of Surgical Oncology 2010 8 48 http content 8 1 48 WORLD JOURNAL OF SURGICAL ONCOLOGY CASE REPORT Open Access Latelocal recurrence of dermatofibrosarcoma protuberans in the skin of female breast Dimitrios M Dragoumis 1 Leda-Aikaterini K Katsohi1 loannis K Amplianitis2 and Aris PTsiftsoglou1 Abstract Dermatofibrosarcoma protuberans DFSP of the breast is exceptionally obscure and late local recurrence of this entity on this site is even more uncommon. We describe such a case in a 48-year-old woman who at the age of 35 had a DFSP excised from her right breast. Thirteen years later she developed an ovoid mass in her right breast over the postsurgical scar area. Wide local excision of the tumor with generous tissue margin was performed and microscopic and immunohistochemical findings established the diagnosis of recurrent DFSP No further treatment was administered and she remains well 18 months later without tumor recurrence. We report an exceptionally rare case of local recurrence of DFSP in the female breast and discuss in detail the diagnostic and therapeutic implications of this pathology. Introduction Dermatofibrosarcoma protuberans DFSP is a relatively uncommon neoplasm of the deep dermis and subcutaneous tissue with low-grade malignant potential. Although DFSP may have been reported in the medical literature as early as 1890 this entity was initially described by Darier and Ferrand in 1924 and was referred as progressive and recurring dermatofibroma . In 1925 Hoffman delineated the clinicopathologic features of this lesion which he officially termed dermatofibrosarcoma protuberans 1 . The clinical behavior of DFSP is characterized by progressive local growth and a propensity for local recurrence. DFSP most commonly appears on the trunk and the extremities and it frequently looks like a benign lesion. When it occurs over the breast it can be difficult to distinguish from a primary breast lesion. Recent findings from the
