Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Repeat hepatectomy for recurrent hepatocellular carcinoma: a local experience and a systematic review | Zhou et al. World Journal of Surgical Oncology 2010 8 55 http content 8 1 55 RESEARCH WORLD JOURNAL OF SURGICAL ONCOLOGY Open Access Repeat hepatectomy for recurrent hepatocellular carcinoma a local experience and a systematic review Yanming Zhou21 2 Chengjun Sui 2 Bin Li1 Zhengfeng Yin 3 Yunchang Tan2 Jiamei Yang 2 and Zhenyu Liu3 Abstract Background This study aimed to assess the efficacy and safety of repeat hepatectomy for recurrent hepatocellular carcinoma HCC . Methods Thirty-seven patients who underwent a curative repeat hepatectomy in our hospital were retrospectively studied. An extensive database literature search was performed to obtain for all relevant studies. Results In our series there were no perioperative deaths during repeat hepatectomy for recurrent HCC. Patients survival after repeat hepatectomy were similar to 429 patients undergoing initial hepatectomy. A computerized search of the Medline and PubMed databases found 29 retrospective studies providing relevant data in 1149 patients were included for appraisal and data extraction. After the repeat hepatectomy postoperative morbidity ranged from to with a median per cohort of per cent. There were 7 perioperative deaths per cent of 993 for whom mortality data were provided . The overall median survival ranged from 21 to months with 1 - 3 - and 5-year survival of to 100 to and to respectively. Conclusions Repeat hepatectomy can be performed safely and is associated with long-term survival in a subset of patients with recurrent HCC. However the findings have to be carefully interpreted due to the lower level of evidence. A randomized controlled study is needed to compare repeat hepatectomy and other modalities for recurrent HCC. Background Hepatocellular carcinoma HCC is the fifth most common cancer in the world responsible for 500 000 deaths globally every year and its incidence is increasing worldwide because of the dissemination of .
