Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Intraabdominal and retroperitoneal soft-tissue sarcomas - outcome of surgical treatment in primary and recurrent tumors | Sogaard et al. World Journal of Surgical Oncology 2010 8 81 http content 8 1 81 WORLD JOURNAL OF SURGICAL ONCOLOGY RESEARCH Open Access Intraabdominal and retroperitoneal soft-tissue sarcomas - outcome of surgical treatment in primary and recurrent tumors 1 1 12 1 3 Ane S Sogaard Jacob M Laurberg Mette Sorensen Ole S Sogaard Pal Wara Peter Rasmussen Soren Laurberg 3 Abstract Background Surgery is the only curative treatment for intraabdominal and retroperitoneal sarcoma IaRS . Little is known about how to treat patients with recurrence. We here report the outcome in primary and recurrent sarcoma treated at the Sarcoma Center in Aarhus Denmark. Methods All patients evaluated for IaRS from June 1998 to May 2008 were enrolled and data on symptoms signs means of diagnosis extent of surgery perioperative complications mortality and long time survival were registered. Primary and first-recurrence sarcomas were analyzed separately. Results Sixty-five of 73 primary and 22 of 28 first-recurrence IaRS had surgery. Fifty-three 82 and 11 50 patients achieved radical R0 resection. Age and radicality of surgery were independent predictors of death while recurrence of sarcoma was not. Perioperative mortality was . 5-year survival was for primary and for first-recurrent sarcomas. However patients with radical surgery had 5-year survival of over 70 in both the primary and recurrent group. Conclusions The radicality of surgery is the most important prognostic factor. Patients with recurrence have an equally good prognosis as those with primary sarcoma if radicality is achieved and such surgery should not be considered only as a palliative effort. Background Soft tissue sarcomas are a heterogeneous group of malignant tumors originating from mesenchymal cells. They constitute just under 1 of all cancers 1 corresponding to only 9000 new cases annually in US and 1500 in UK 1 2 . Approximately 20 of soft tissue sarcomas arise from intraabdominal or .
