Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Surgical treatment for locally advanced lower third rectal cancer after neoadjuvent chemoradiation with capecitabine: prospective phase II trial | World Journal of Surgical Oncology o BioMed Central Surgical treatment for locally advanced lower third rectal cancer after neoadjuvent chemoradiation with capecitabine prospective phase II trial Mostafa Abd Elwanis1 Doaa W Maximous2 Mohamed Ibrahim Elsayed1 and Nabiel NH Mikhail 3 Address Department of Radiotherapy South Egypt Cancer Institute Assiut Egypt 2Department of Surgical Oncology South Egypt Cancer Institute Assiut Egypt and 3Department of Biostatistics and Cancer Epidemiology South Egypt Cancer Institute Assiut Egypt Email Mostafa Abd Elwanis - mostafawanis@ Doaa W Maximous - doaawadie@ Mohamed Ibrahim Elsayed - mohebel@ Nabiel NH Mikhail - nabiel@ Corresponding author Published 9 June 2009 Received 10 April 2009 World Journal of Surgical Oncology 2009 7 52 doi 1477-7819-7-52 Accepted 9 June 2009 This article is available from http content 7 1 52 2009 Elwanis et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Treatment of rectal cancer requires a multidisciplinary approach with standardized surgical pathological and radiotherapeutic procedures. Sphincter preserving surgery for cancer of the lower rectum needs a long-course of neoadjuvant treatments to reduce tumor volume to induce down-staging that increases circumferential resection margin and to facilitate surgery. Aim To evaluate the rate of anal sphincter preservation in low lying resectable locally advanced rectal cancer and the resectability rate in unresectable cases after neoadjuvent chemoradiation by oral Capecitabine. Patients and methods This trial included 43 patients with low lying 4-7 cm from anal verge locally advanced rectal cancer of which 33 were .
