Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Frontal skull craniotomy combined with moderate-dose radiotherapy effectively ameliorate a rare case of non-secretory, multiple myeloma with orbital involvement | World Journal of Surgical Oncology BioMed Central Open Access Case report Frontal skull craniotomy combined with moderate-dose radiotherapy effectively ameliorate a rare case of non-secretory multiple myeloma with orbital involvement Hui-Ling Ko1 Ching-Lin Chen 2 and Kwan-Hwa Chi1 Address Departments of Radiation Therapy and Oncology Taipei Taiwan and 2Department of Neurosurgery Shin Kong Memorial Hospital Taipei Taiwan Email Hui-Ling Ko - writing_y@ Ching-Lin Chen - komdms@ Kwan-Hwa Chi - nowebmail@ Corresponding author Published 12 November 2009 Received I June 2009 __ rr. inAO Accepted 12 November 2009 World Journal of Surgical Oncology 2009 7 86 doi 1477-7819-7-86 This article is available from http content 7 1 86 2009 Ko et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Orbital infiltration in patients with multiple myeloma is a rare condition with less than 50 cases reported in the medical literature. Most patients undergo conservative treatment because multiple myeloma is a disseminated systemic disease. Case presentation A 43-year-old male subject with multiple myeloma and long-term survival presented with orbital involvement. The subject lacked the typical features and poor prognostic factors associated with multiple myeloma such as renal failure hypercalcemia and paraprotein in the serum and urine. The orbital computed tomographic scan revealed the tumor encasing the optic nerve but without prominent bony destruction. Therefore a frontal skull craniotomy with an epidural entrance to the orbital space was performed to completely extirpate the orbital mass. The surgical procedure was followed by moderate-dose .
