Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Atypical presentation of angiosarcoma of the scalp in the setting of Human Immunodeficiency Virus (HIV) | World Journal of Surgical Oncology BioMed Central Open Access Case report Atypical presentation of angiosarcoma of the scalp in the setting of Human Immunodeficiency Virus HIV Poovandren S Govender Address Department of Radiotherapy and Oncology Nelson R. Mandela School of Medicine University of Kwazulu Natal Durban South Africa Email Poovandren S Govender - Published 18 December 2009 Received 31 October 2009 World Journal of Surgical Oncology 2009 7 99 doi l477-78l 9-7-99 Accepted 18 December 2009 This article is available from http content 7 l 99 2009 Govender licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Angiosarcoma of the head and neck is an uncommon aggressive malignant entity most commonly found in elderly Caucasian males. We present a case in a young black female with co-existing HIV. The atypical gender age and race of the patient reflect the unusual clinical presentation of this case of angiosarcoma attributable to the patient s HIV status. Case presentation A 22 year old patient presented with a large unresectable lesion over the occiput with surrounding ulceration satellite lesions and associated lymphadenopathy. She is HIV-infected with a CD4 count of 360 cells pl. She was not on antiretroviral treatment based on South African treatment guidelines advocating antiretroviral treatment when the CD4 count is below 200 cells pl in the absence of other AIDS-defining illnesses. The patient was treated with a course of ifosfamide and anthracyline based chemotherapy. Disease progression was noted on chemotherapy and she was subsequently palliated with a course of radiotherapy. She had a satisfactory response with an improvement in local symptoms. She is .
