Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài:Interleukin-7 deficiency in rheumatoid arthritis: consequences for therapy-induced lymphopenia. | Available online http content 7 1 R80 Research article Interleukin-7 deficiency in rheumatoid arthritis consequences for therapy-induced lymphopenia Frederique Ponchel1 2 Robert J Verburg3 Sarah J Bingham2 Andrew K Brown2 John Moore4 Andrew Protheroe5 Kath Short5 Catherine A Lawson1 2 Ann W Morgan1 2 Mark Quinn2 Maya Buch2 Sarah L Field1 Sarah L Maltby1 Aurelie Masurel1 Susan H Douglas1 Liz Straszynski1 Ursula Fearon2 Douglas J Veale2 Poulam Patel5 Dennis McGonagle2 John Snowden6 Alexander F Markham1 David Ma4 Jacob M van Laar3 Helen A Papadaki7 Paul Emery2 and John D Isaacs1 2 8 Molecular Medicine Unit University of Leeds Leeds UK 2Academic Unit of Musculoskeletal Disease Leeds General Infirmary Leeds UK 3Department of Rheumatology Leiden University Medical Center Leiden The Netherlands 4Hematology Department St Vincent Hospital Sydney Australia 5Cancer Research UK University of Leeds Leeds UK 6Department of Haematology Royal Hallamshire Hospital Sheffield UK 7Department of Hematology University of Crete School of Medicine Heraklion Crete Greece 8School of Clinical Medical Sciences Musculoskeletal Research Group The University of Newcastle Newcastle upon Tyne UK Corresponding author Frederique Ponchel Received 3 Aug 2004 Revisions requested 9 Sep 2004 Revisions received 15 Sep 2004 Accepted 27 Sep 2004 Published 16 Nov 2004 Arthritis Res Ther 2005 7 R80-R92 DOI ar1452 2004 Ponchel et al. licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is cited. Open Access Abstract We previously demonstrated prolonged profound CD4 T-lymphopenia in rheumatoid arthritis RA patients following lymphocyte-depleting therapy. Poor reconstitution could result either from reduced de novo T-cell production through .
