Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài:Quantitative ultrasonic assessment for detecting microscopic cartilage damage in osteoarthritis. | Available online http content 7 1 R38 Research article Quantitative ultrasonic assessment for detecting microscopic cartilage damage in osteoarthritis Koji Hattori1 Ken Ikeuchi2 Yusuke Morita2 and Yoshinori Takakura1 Open Access Department of Orthopaedic Surgery Nara Medical University Kashihara Nara Japan institute for Frontier Medical Sciences Kyoto University Kyoto Japan Corresponding author Koji Hattori hattori@ Received 4 Aug 2004 Revisions requested 1 Oct 2004 Revisions received 9 Oct 2004 Accepted 16 Oct 2004 Published 16 Nov 2004 Arthritis Res Ther 2005 7 R38-R46 DOI ar1463 2004 Hattori et al. licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Osteoarthritis OA is one of the most prevalent chronic conditions. The histological cartilage changes in OA include surface erosion and irregularities deep fissures and alterations in the staining of the matrix. The reversibility of these chondral alterations is still under debate. It is expected that clinical and basic science studies will provide the clinician with new scientific information about the natural history and optimal treatment of OA at an early stage. However a reliable method for detecting microscopic changes in early OA has not yet been established. We have developed a novel system for evaluating articular cartilage in which the acoustic properties of the articular cartilage are measured by introducing an ultrasonic probe into the knee joint under arthroscopy. The purpose of this study was to assess microscopic cartilage damage in OA by using this cartilage evaluation system on collagenase-treated articular cartilage in vivo and in vitro. Ultrasonic echoes from articular cartilage were converted into a wavelet
