Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Substernal oxyphil parathyroid adenoma producing PTHrP with hypercalcemia and normal PTH level | BioMed Central World Journal of Surgical Oncology Open Access Substernal oxyphil parathyroid adenoma producing PTHrP with hypercalcemia and normal PTH level Angela Gurrado1 Andrea Marzullo2 Germana Lissidini1 Agostino Lippolis1 Domenico Rubini3 Gaetano Lastilla2 and Mario Testini 1 Address Department of Applications in Surgery of Innovative Technologies University Medical School of Bari Italy 2Department of Pathology University Medical School of Bari Italy and 3Department of Nuclear Medicine University Medical School of Bari Italy Email Angela Gurrado - angelagurrado@ Andrea Marzullo - Germana Lissidini - germanalissidini@ Agostino Lippolis - Domenico Rubini - Gaetano Lastilla - Mario Testini - Corresponding author Published 21 February 2008 Received 8 December 2007 __ rr. AAAO .u J -IA I I o z í I All -TO IA z A A Accepted 21 February 2008 World Journal of Surgical Oncology 2008 6 24 doi l477-78l9-6-24 This article is available from http content 6 l 24 2008 Gurrado et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Parathyroid adenoma is the most common cause of primary hyperparathyroidism. Preoperative serum calcium and intact-parathyroid hormone levels are the most useful diagnostic parameters that allow differentiating primary hyperparathyroidism from non-parathyroiddependent hypercalcemia. Parathyroidectomy is the definitive treatment for primary hyperparathyroidism. Approximately 5 of patients who underwent parathyroidectomy present with persistent or recurrent hyperparathyroidism due to ectopic localization of the adenoma. Functioning oxyphil .