Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: A multidisciplinary approach for the treatment of GIST liver metastasis | World Journal of Surgical Oncology BioMed Central Open Access Case report A multidisciplinary approach for the treatment of GIST liver metastasis Pejman Radkani Marcelo M Ghersi Juan C Paramo and Thomas W Mesko Address Department of Surgery Section of Surgical Oncology Mount Sinai Medical Center Miami Beach Florida USA Email Pejman Radkani - pejman_radkani@ Marcelo M Ghersi - mmghersi@ Juan C Paramo - jcparamo@ Thomas W Mesko - dr-mesko@ Corresponding author Published 9 May 2008 Received 23 October 2007 World Journal of Surgical Oncology 2008 6 46 doi 1477-7819-6-46 Accepted 9 May 2008 This article is available from http content 6 1 46 2008 Radkani et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Advanced gastrointestinal stromal tumors GISTs can metastasize and recur after a long remission period resulting in serious morbidity mortality and complex management issues. Case presentation A 67-year-old woman presented with epigastric fullness mild jaundice and weight loss with a history of a bowel resection 7 years prior for a primary GIST of the small bowel. The finding of a heterogeneous mass cm in diameter replacing most of the left lobe of the liver by ultrasonography and CT followed by positive cytological studies revealed a metastatic GIST. Perioperative optimization of the patient s nutritional status along with biliary drainage and portal vein embolization were performed. Imatinib was successful in reducing the tumor size and facilitating surgical resection. Conclusion A well-planned multidisciplinary approach should be part of the standard management of advanced or metastatic GIST. Background Gastrointestinal stromal tumors GISTs .
