Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: An unusual case of low-grade tubulopapillary adenocarcinoma of the sinonasal tract | BioMed Central World Journal of Surgical Oncology Open Access Case report An unusual case of low-grade tubulopapillary adenocarcinoma of the sinonasal tract Ashish Bansal 1 Keloth E Pradeep2 and Krishna P Gumparthy1 Address Department of Histopathology Wirral Hospitals NHS Trust Upton Wirral CH49 5PE UK and 2Department of Histopathology Wrexham Maelor Hospital Wrexham UK Email Ashish Bansal - ask4ashish@ Keloth E Pradeep - pradeepke@ Krishna P Gumparthy - Corresponding author Published 20 May 2008 Received 3 November 2007 World Journal of Surgical Oncology 2008 6 54 doi 1477-7819-6-54 Accepted 20 May 2008 This article is available from http content 6 1 54 2008 Bansal et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Low-grade papillary adenocarcinomas of the sinonasal tract are rare neoplasms. Over recent years little doubt remains that this tumour represents a separate entity based on morphology ultrastructural features and behaviour. We outline a case of this rare entity displaying a not hitherto described immunophenotype. Case presentation A 32 year old man presented recurrent epistaxis was evaluated with endoscopy which revealed a well circumscribed pedunculated mass lesion in left nares. The mass was arising from the nasal septum which was excised along with the mass. The biopsy revealed low-grade non-intestinal type sinonasal tubulopapillary adenocarcinoma. Conclusion TTF-I immunoreactivity in absence of thyroid or pulmonary primary in the present case remains an enigma. However this raises the possibility of the utility of this antibody to predict a better clinical outcome in the subset of low grade non-intestinal sinonasal .
