Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Helicobacter pylori and gastroesophageal reflux disease | BioMed Central World Journal of Surgical Oncology Research Helicobacter pylori and gastroesophageal reflux disease Michele Grande Federica Cadeddu Massimo Villa Grazia Maria Attinà Marco Gallinella Muzi Casimiro Nigro Francesco Rulli and Attilio M Farinon Open Access Address Department of Surgery University Hospital Tor Vergata Rome Italy Email Michele Grande - grande@ Federica Cadeddu - Massimo Villa - massimo@ Grazia Maria Attinà - Marco Gallinella Muzi - Casimiro Nigro - Francesco Rulli - Attilio M Farinon - farinon@ Corresponding author Published 5 July 2008 Received 30 December 2007 World Journal of Surgical Oncology 2008 6 74 doi 1477-7819-6-74 Accepted 5 July 2008 This article is available from http content 6 1 74 2008 Grande et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The nature of the relationship between Helicobacter pylori and reflux oesophagitis is still not clear. To investigate the correlation between Helicobacter pylori infection and GERD taking into account endoscopic pH-metric and histopathological data. Methods Between January 2001 and January 2003 a prospective study was performed in 146 patients with GERD in order to determine the prevalence of Helicobacter pylori infection at gastric mucosa further the value of the De Meester score endoscopic manometric and pH-metric parameters . reflux episodes pathological reflux episodes and extent of oesophageal acid exposure of the patients with and without Helicobacter pylori infection were studied and statistically compared. Finally univariate analysis of the
