Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Correlation of HER-2 over-expression with clinico-pathological parameters in Tunisian breast carcinoma | BioMed Central World Journal of Surgical Oncology Research Correlation of HER-2 over-expression with clinico-pathological parameters in Tunisian breast carcinoma Lobna Ayadi 1 Abdelmajid Khabir1 Habib Amouri2 Sondes Karray3 Abdallah Dammak2 Mohamed Guermazi2 and Tahya Boudawara1 Address Department of Pathology Habib Bourguiba University Hospital Sfax Tunisia 2Department of Gynecology Hedi Chaker University Hospital Sfax Tunisia and 3Center of Biotechnology Sfax Tunisia Email Lobna Ayadi - ayadilobna@ Abdelmajid Khabir - akabdelmajid@ Habib Amouri - amouri_hab@ Sondes Karray - Abdallah Dammak - abdallah@ Mohamed Guermazi - med_guer@ Tahya Boudawara - Corresponding author Open Access Published 22 October 2008 Received 13 May 2008 World Journal of Surgical Oncology 2008 6 112 doi 1477-7819-6-112 Accepted 22 October 2008 This article is available from http content 6 1 112 2008 Ayadi et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract_ Background Breast carcinoma is a disease with a tremendous heterogeneity in its clinical behavior. Newer prognostic factors and predictors of response to therapy are needed. The aim of this study was to evaluate the expression of HER-2 estrogen receptor ER and progesterone receptors PR in breast carcinoma and to compare it with other prognostic parameters such as histological type and grade tumor size patients age and lymph node metastases. Patients and methods This is a retrospective study conducted in the department of pathology at Sfax University Hospital. Confirmed 155 Cases of breast carcinoma were .
