Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: A study of lymph node ratio in stage IV colorectal cancer | BioMed Central World Journal of Surgical Oncology Open Access A study of lymph node ratio in stage IV colorectal cancer Kristoffer Derwinger and Bengt Gustavsson Address Department of Surgery Sahlgrenska University Hospital Ostra Gothenburg Sweden Email Kristoffer Derwinger - Bengt Gustavsson - Corresponding author Published I December 2008 Received 10 April 2008 _I- -7 noziumoio Í I- - Accepted 1 December 2008 World Journal of Surgical Oncology 2008 6 127 doi 186 1477-7819-6-127 This article is available from http content 6 1 127 2008 Derwinger and Gustavsson licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The finding of metastasis in colorectal cancer stage IV disease has a major impact on prognosis and treatment strategy. Known important factors include the extent of the metastasis and the patients performance status. The lymph node factors are of known importance in earlier cancer stages but less described in metastatic disease. The aim of the study was to evaluate lymph node status and ratio as prognostic markers in stage IV colorectal cancer. Methods The study was retrospective and assessing all patients operated with bowel resection for an initial stage IV colorectal cancer during 1999-2003 n 1 36 . Basic demographic data as well as given treatment was assessed. The Lymph node ratio LNR the quota between the number of lymph node metastasis and assessed lymph nodes was calculated. LNR groups were created by ratio thirds 3 equally sized groups. The analysis was made by LNR group and by eligibility for chemotherapy with cancer specific survival as outcome parameter. Results The median survival CSS for the .
