Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: A paraneoplastic manifestation of metastatic breast cancer responding to endocrine therapy: a case report | World Journal of Surgical Oncology BioMed Central Open Access A paraneoplastic manifestation of metastatic breast cancer responding to endocrine therapy a case report Joanna P Wood1 Andrew P Haynes2 and KL Cheung 3 Address Department of Medical Oncology City Hospital Nottingham University Hospitals NHS trust Nottingham UK 2Department of Medicine City Hospital Nottingham University Hospitals NHS Trust Nottingham UK and 3Division of Breast Surgery Nottingham University Hospitals NHS trust University of Nottingham Nottingham UK Email Joanna P Wood - joeywood@ Andrew P Haynes - ahaynes@ KL Cheung - Corresponding author Published 16 December 2008 Received 24 July 2008 __ rr. inAO - - I Accepted 16 December 2008 World Journal of Surgical Oncology 2008 6 132 doi 186 1477-7819-6-132 This article is available from http content 6 1 132 2008 Wood et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Many cancers are known to be associated with paraneoplastic syndromes. These syndromes are usually treated by chemotherapy with or without immunosupression but they often respond poorly. There are no published reviews on response to endocrine treatment. Case presentation We report a case of a patient presenting with papillitis myositis and sensory peripheral neuropathy 18 months before a diagnosis of metastatic oestrogen receptor positive breast cancer was confirmed. The patient was treated with anastrozole which led not only to a decrease of her tumour burden but also to an improvement in her biochemical markers and amelioration of her clinical symptoms. Conclusion This case is an example of breast cancer presenting with .
