Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Expression of bioactive bone morphogenetic proteins in the subacromial bursa of patients with chronic degeneration of the rotator cuff. | Available online http content 8 4 R92 Research article Expression of bioactive bone morphogenetic proteins in the subacromial bursa of patients with chronic degeneration of the rotator cuff Jana Neuwirth1 Renée AE Fuhrmann1 Amanda Veit1 Matthias Aurich1 Ilmars Stonâns1 Tilo Trommer1 Peter Hortschansky2 Susanna Chubinskaya3 and Juergen A Mollenhauer1 3 Department of Orthopedics University of Jena Klosterlausnitzerstr. 81 D-07607 Eisenberg 2Leibniz Institute for Natural Product Research and Infection Biology Hans-Knoll Institute Beutenbergstr. 11a D-07745 Jena 3Department of Biochemistry Rush University Medical Center 1653 W. Congress Parkway Chicago IL 6061 2 USA Corresponding author Juergen A Mollenhauer Received 10 Oct 2005 Revisions requested 27 Oct 2005 Revisions received 7 Apr 2006 Accepted 24 Apr 2006 Published 23 May 2006 Arthritis Research Therapy 2006 8 R92 doi ar1 965 This article is online at http content 8 4 R92 2006 Neuwirth et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Degeneration of the rotator cuff is often associated with inflammation of the subacromial bursa and focal mineralization of the supraspinatus tendon. Portions of the supraspinatus tendon distant from the insertion site could transform into fibrous cartilage causing rotator-cuff tears owing to mechanical instability. Indirect evidence is presented to link this pathology to ectopic production and secretion of bioactive bone morphogenetic proteins BMPs from sites within the subacromial bursa. Surgically removed specimens of subacromial bursa tissue from patients with chronic tears of the rotator cuff were analyzed by .
