Báo cáo y học: "Presence of antibodies against cyclic citrullinated peptides in patients with 'rhupus': a cross-sectional study"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Presence of antibodies against cyclic citrullinated peptides in patients with 'rhupus': a cross-sectional study. | Available online http content 8 5 R144 Open Access Research article Presence of antibodies against cyclic citrullinated peptides in patients with rhupus a cross-sectional study Luis M Amezcua-Guerra1 Rashidi Springall1 Ricardo Marquez-Velasco1 Lorena Gomez-Garcia1 Angelica Vargas2 and Rafael Bojalil1 3 1 Department of Immunology Instituto Nacional de Cardiologia Ignacio Chavez Juan Badiano 1 Sección XVI Tlalpan 14080 Mexico City Mexico 2Department of Rheumatology Instituto Nacional de Cardiologia Ignacio Chavez Juan Badiano 1 Sección XVI Tlalpan 14080 Mexico City Mexico 3Department of Health Care Universidad Autónoma Metropolitana Xochimilco Calzada del Hueso 11 00 Villa Quietud Coyoacán 04960 Mexico City Mexico Corresponding author Rafael Bojalil bojraf@ Received 14 Jul 2006 Revisions requested 9 Aug 2006 Revisions received 15 Aug 2006 Accepted 25 Aug 2006 Published 25 Aug 2006 Arthritis Research Therapy 2006 8 R144 doi ar2036 This article is online at http content 8 5 R144 2006 Amezcua-Guerra et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Rhupus is a rare condition sharing features of rheumatoid arthritis RA and systemic lupus erythematosus SLE . If rhupus is a distinctive entity an overlap between RA and SLE or a subset of SLE is currently debated. This study was performed to explore the prevalence of antibodies against cyclic citrullinated peptides anti-CCP antibodies in rhupus. Patients meeting American College of Rheumatology criteria for RA SLE or both were included. Clinical and radiographic features were recorded and sera were searched for anti-CCP antibodies rheumatoid factor antinuclear antibodies anti-extractable nuclear antigens and

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