Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: Dosimetric comparison using different multileaf collimeters in intensity-modulated radiotherapy for upper thoracic esophageal cancer. | Gong et al. Radiation Oncology 2010 5 65 http content 5 1 65 RADIATION ONCOLOGY RESEARCH Open Access Dosimetric comparison using different multileaf collimeters in intensity-modulated radiotherapy for upper thoracic esophageal cancer Youling Gong21 Shichao Wang 22 Lin Zhou1 Yongmei Liu1 Yong Xu1 You Lu1 Sen Bai2 Yuchuan Fu2 Qingfeng Xu2 and Qingfeng Jiang2 Abstract Purpose To study the impacts of multileaf collimators MLC width standard MLC width of 10 mm sMLC and micro-MLC width of 4 mm mMLC in the intensity-modulated radiotherapy IMRT planning for the upper thoracic esophageal cancer UTEC . Methods and materials 10 patients with UTEC were retrospectively planned with the sMLC and the mMLC. The monitor unites MUs and dose volume histogram-based parameters conformity index CI and homogeneous index HI were compared between the IMRT plans with sMLC and with mMLC. Results The IMRT plans with the mMLC were more efficient average MUs than plans with the sMLC average MUs p . Also compared to plans with the sMLC the plans with the mMLC showed advantages in dose coverage of the planning gross tumor volume Pgtv CI HI and the planning target volume PTV CI HI p . In addition the significant dose sparing in the D5 vs gEUD vs of the spinal cord the V10 vs V20 vs MLD vs and gEUD vs of the lungs were observed in the plans with the mMLC respectively p . Conclusions Comparing to the sMLC the mMLC not only demonstrated higher efficiencies and more optimal target coverage but also considerably improved the dose sparing of OARs in the IMRT planning for UTEC. Introduction Upper thoracic esophageal carcinoma UTEC occurs rarely and accounts for only 5 -10 of all esophageal carcinomas in 1 . Surgery operation has not been an appropriate .
