Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: Feasibility study of volumetric modulated arc therapy for the treatment of retroperitoneal sarcomas. | Llacer-Moscardo et al. Radiation Oncology 2010 5 83 http content 5 1 83 RADIATION ONCOLOGY RESEARCH Open Access Feasibility study of volumetric modulated arc therapy for the treatment of retroperitoneal sarcomas Carmen Llacer-Moscardo1 Frangois Quenet2 David Azria1 Pascal Fenoglietto1 Abstract Background Radiotherapy for retroperitoneal sarcomas remains controversial and a technical challenge considering the threshold of contiguous critical organs tolerance. We performed consecutive RapidArc dosimetric plans in preoperative or postoperative setting. Methods A dosimetric study was carried out from six preoperative group A and four postoperative group B CT-scans performed in 7 patients. Prescribed dose was 45 and 50 Gy for groups A and B respectively. The planning target volume PTV was defined as the clinical target volume CTV plus 5 mm. The CTV encompassed the gross tumor volume GTV plus 10 mm or the tumoral bed. The dosimetric plans were optimized on a RapidArc Eclipse console using the progressive resolution algorithm PRO version . Normalization method allowed the coverage of 99 of the PTV by 95 of the dose. Results Mean PTV were cc range 348-6198 cc and cc range 463 -933 cc for groups A and B respectively. Plans were optimized for single arcs in group B and for single or two arcs in group A. The contralateral kidney volume receiving 5 Gy V5Gy was range 0-55 and range for groups A and B respectively. The mean dose received by 1 of the kidney D1 was Gy range Gy for group A and Gy range Gy for group B. The volume of small bowel excluding the PTV small bowel-PTV that received 40 Gy and 30 Gy V40Gy and V30Gy in group A were range and range respectively. In group B small bowel-PTV V40Gy and V30Gy were range and range respectively. In a second step we treated two patients in the postoperative group. .
