Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: Accelerated Partial Breast Irradiation (APBI): A review of available techniques. | Njeh et al. Radiation Oncology 2010 5 90 http content 5 1 90 RADIATION ONCOLOGY REVIEW Open Access Accelerated Partial Breast Irradiation APBI A review of available techniques Christopher F Njeh1 t Mark W SaundersH Christian M _angton2t Abstract Breast conservation therapy BCT is the procedure of choice for the management of the early stage breast cancer. However its utilization has not been maximized because of logistics issues associated with the protracted treatment involved with the radiation treatment. Accelerated Partial Breast Irradiation APBI is an approach that treats only the lumpectomy bed plus a 1-2 cm margin rather than the whole breast. Hence because of the small volume of irradiation a higher dose can be delivered in a shorter period of time. There has been growing interest for APBI and various approaches have been developed under phase I-III clinical studies these include multicatheter interstitial brachytherapy balloon catheter brachytherapy conformal external beam radiation therapy and intraoperative radiation therapy IORT . Balloon-based brachytherapy approaches include Mammosite Axxent electronic brachytherapy and Contura Hybrid brachytherapy devices include SAVI and ClearPath. This paper reviews the different techniques identifying the weaknesses and strength of each approach and proposes a direction for future research and development. It is evident that APBI will play a role in the management of a selected group of early breast cancer. However the relative role of the different techniques is yet to be clearly identified. Introduction Breast cancer is a worldwide problem accounting for of all cancer incidence among women making it the second most common type of non-skin cancer after lung cancer and the fifth most common cause of cancer death. In the USA breast cancer has the highest incidence among all cancer types in females with one in every eight to ten women being affected during her lifetime 1 it is estimated that
