Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: Application of volumetric modulated arc therapy (VMAT) in a dual-vendor environment. | Dobler et al. Radiation Oncology 2010 5 95 http content 5 1 95 RADIATION ONCOLOGY RESEARCH Open Access Application of volumetric modulated arc therapy VMAT in a dual-vendor environment Barbara Dobler Karin Weidner Oliver Koelbl Abstract Background and Purpose The purpose of this study was to assess plan quality and treatment time achievable with the new VMAT optimization tool implemented in the treatment planning system Oncentra MasterPlan as compared to IMRT for Elekta SynergyS linear accelerators. Materials and methods VMAT was implemented on a SynergyS linear accelerator Elekta Ltd. Crawley UK with Mosaiq record and verify system IMPAC Medical Systems Sunnyvale CA and the treatment planning system Oncentra MasterPlan Nucletron BV Veenendaal the Netherlands . VMAT planning was conducted for three typical target types of prostate cancer hypopharynx larynx cancer and vertebral metastases and compared to standard IMRT with respect to plan quality number of monitor units MU and treatment time. Results For prostate cancer and vertebral metastases single arc VMAT led to similar plan quality as compared to IMRT. For treatment of the hypopharynx larynx cancer a second arc was necessary to achieve sufficient plan quality. Treatment time was reduced in all cases to 35 to 43 as compared to IMRT. Times required for optimization and dose calculation however increased by a factor of to . Conclusion Similar or improved plan quality can be achieved with VMAT as compared to IMRT at reduced treatment times but increased calculation times. Background Volumetric modulated arc therapy VMAT allows irradiation with simultaneously varying dose rate gantry speed collimator and leaf positions. It has been first introduced by Otto in 2008 1 and implemented for Varian linear accelerators as RapidArc 2-8 . Various treatment planning studies have been published comparing RapidArc and dynamic intensity modulated radiation therapy IMRT or conventional stereotactic .
