Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: Evaluation of volumetric modulated arc therapy (VMAT) with Oncentra . | Alvarez-Moret et al. Radiation Oncology 2010 5 110 http content 5 1 110 RADIATION ONCOLOGY RESEARCH Open Access Evaluation of volumetric modulated arc therapy VMAT with Oncentra MasterPlan for the treatment of head and neck cancer Judith Alvarez-Moret Fabian Pohl Oliver Koelbl Barbara Dobler Abstract Background Several comparison studies have shown the capability of VMAT to achieve similar or better plan quality as IMRT while reducing the treatment time. The experience of VMAT in a multi vendor environment is limited. We compared the plan quality and performance of VMAT to IMRT and we investigate the effects of varying various user-selectable parameters. Methods IMRT single arc VMAT and dual arc VMAT were compared for four different head-and-neck tumors. For VMAT the effect of varying gantry angle spacing and treatment time on the plan quality was investigated. A comparison of monitor units and treatment time was performed. Results IMRT and dual arc VMAT achieved a similar plan quality while single arc could not provide an acceptable plan quality. Increasing the number of control points does not improve the plan quality. Dual arc VMAT delivery time is about 30 of IMRT delivery time. Conclusions Dual arc VMAT is a fast and accurate technique for the treatment of head and neck cancer. It applies similar number of MUs as IMRT but the treatment time is strongly reduced maintaining similar or better dose conformity to the PTV and OAR sparing. Background Intensity modulated radiotherapy IMRT is the standard external radiotherapy technique to treat head-and-neck tumors because of the clinical benefits of parotid glands and spinal cord sparing 1-5 . Volumetric arc therapy VMAT is an extension of IMRT which allows irradiation with simultaneously changing multileaf-collimator MLC position gantry position and dose rate 6 . Various treatment planning studies have been published showing the potential of VMAT to reduce treatment time without compromising plan
