Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: Carbon ion therapy for ameloblastic carcinoma. | Jensen et al. Radiation Oncology 2011 6 13 http content 6 1 13 RADIATION ONCOLOGY CASE REPORT Open Access Carbon ion therapy for ameloblastic carcinoma 1 2 2 1 1 1 Alexandra D Jensen Swantje Ecker Malte Ellerbrock Anna Nikoghosyan Jurgen Debus Marc W Munter Abstract Ameloblastic carcinomas are rare odontogenic tumors. Treatment usually consists of surgical resection and sometimes adjuvant radiation. We report the case of a 71 year-old male patient undergoing carbon ion therapy for extensive local relapse of ameloblastic carcinoma. Treatment outcome was favourable with a complete remission at 6 weeks post completion of radiotherapy while RT-treatment itself was tolerated well with only mild side effects. High dose radiation hence is a potential alternative for patients unfit or unwilling to undergo extensive surgery or in cases when only a subtotal resection is planned or the resection is mutilating. Introduction Ameloblastic carcinomas are very rare odontogenic tumors sometimes referred to as malignant ameloblastoma 1 . To date 31 cases have been reported worldwide with the largest series describing 14 cases 2 Definitions and classifications of ameloblastic carcinomas have changed over the years there have been various classifications the latest by Slootweg and Muller 3 emphasizing histogenesis of the tumor leading to the new WHO classification in 2005 4 . Slootweg and Muller defined ameloblastic carcinoma as a tumor combining morphologic features of both ameloblastoma and carcinoma which can arise de novo ex ameloblastoma or ex odontogenic cyst 3 . Most of the reported cases were discovered in the mandible only one fifth occur in the maxilla 5 6 . Though they claimed to exhibit a tendency towards aggressive local growth and local relapse 1 distant metastases are uncommon. Being a rare disease there are no treatment guidelines. However standard treatment has been complete surgical resection in reported cases 5 7 . Report of a case A 71-year-old .
