Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: Tangential beam IMRT versus tangential beam 3D-CRT of the chest wall in postmastectomy breast cancer patients: A dosimetric comparison. | Rudat et al. Radiation Oncology 2011 6 26 http content 6 1 26 RADIATION ONCOLOGY RESEARCH Open Access Tangential beam IMRT versus tangential beam 3D-CRT of the chest wall in postmastectomy breast cancer patients A dosimetric comparison x cillcor R id Hit a HdI 11 Alzirzidi 1 Adzz I .Vi Xu rirl l d ìlữd Al-Vzidvzi1 Alfi I i Ziiiri2 Volker Ruddt Abdul Aziz Aldrddi Adel Mundmeu KI Idled AI Idliyd ddlell AUdvvdljll Abstract Background This study evdludtes the dose distribution of reversed pldnned tdngentidl bedm intensity moduldteU radiotherapy IMRT compdred to stdnddrd wedged tdngentidl bedm three-dimensiondlly pldnned conformdl radiotherapy 3D-CRT of the chest wdll in unselected postmdstectomy bredst cdncer pdtients Methods For 20 unselected subsequent postmdstectomy bredst cdncer pdtients tdngentidl bedm IMRT dnd tdngentidl bedm 3D-CRT pldns were generated for the radiotherapy of the chest wdll. The prescribed dose wds 50 Gy in 25 fractions. Dose-volume histograms were evdludted for the PTV dnd orgdns dt risk. Pdrdmeters of the dose distribution were compdred using the Wilcoxon mdtched pdirs test. Results Tdngentidl bedm IMRT stdtisticdlly significdntly reduced the ipsildterdl medn lung dose by dn dverdge of 21 1129 cGy versus 1437 cGy . In dll pdtients tredted on the left side the hedrt volume encompdssed by the 70 isodose line V70 35 Gy wds reduced by dn dverdge of 43 versus dnd the medn hedrt dose by dn dverdge of 20 704 cGy versus 877 cGy . The PTV showed d significdntly better conformity index with IMRT the homogeneity index wds not significdntly different. Conclusions Tdngentidl bedm IMRT significdntly reduced the dose-volume of the ipsildterdl lung dnd hedrt in unselected postmdstectomy bredst cdncer pdtients. Background Breast cancer is the most common cancer in females worldwide. In the United States and Europe the most common treatment is breast conserving surgery followed by adjuvant radiotherapy 1 . In other parts of the world
