Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: Pure seminoma: A review and update. | Boujelbene et al. Radiation Oncology 2011 6 90 http content 6 1 90 RADIATION ONCOLOGY REVIEW Open Access Pure seminoma A review and update I Z S I I Z 1 Z 1 I D Z S I I I 11 2 4A KI f f I f r h I 1 I Z J I D r I 11 Z 1l Z Z Z 3 5 If z I I h V f h V Pl LT4 1 c p. I I c h I I D h Z i t A I 1 Noureddine Boujelbene Adrien Cosinscni Nadia Boujelbene Kaoumar Knanrir snusnila Bnagwan Eveleyn Herrmann1 Rene-Olivier Mirimanoff1 Mahmut Ozsahin1t and AbQerrahim Zouhair 1f Abstract Pure seminoma is a rare pathology of the young adult often discovered in the early stages. Its prognosis is generally excellent and many therapeutic options are available especially in stage I tumors. High cure rates can be achieved in several ways standard treatment with radiotherapy is challenged by surveillance and chemotherapy. Toxicity issues and the patients preferences should be considered when management decisions are made. This paper describes firstly the management of primary seminoma and its nodal involvement and secondly the various therapeutic options according to stage. Keywords Seminoma treatment radiotherapy chemotherapy surveillance Testicular cancers 95 of which are germ-cell tumors GCT are the most common solid malignancies affecting males between the ages of 15 and 35 years although it accounts for only about 1 of all cancers in men 1 . In 2010 it caused an estimated 350 deaths with 8480 new cases diagnosed in the United States alone 1 . In Switzerland and particularly in the Vaud canton its prevalence is one of the world s highest and is still increasing 2 . Nevertheless its origin remains poorly understood although some environmental or genetic risk factors are suspected 3 . It is also known to be bilateral in 3 of cases 4 . GCT may consist of one predominant histologic pattern or represent a mixture of multiple histologic types. For treatment purposes two broad categories are recognized pure seminoma no nonseminomatous elements present and all others which .
